Contact Us

Resources

Publication: Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-AThr288-geminin dual signaling pathways

View or download the Publication to read more
In this study the CERO 3D Incubator & Bioreactor was used to culture A2780 cells and OVCAR5 spheroids in suspension. The researchers showed that LPA can suppress apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promote cell-cycle progression via EGFR-PI3K/Aurora-AThr288-geminin dual signaling pathways. The study provides potential targets for enhancing the clinical benefit of HGSOC precision medicine.

Related Resources

Microfluidic 3D intestine tumor spheroid model for efficient in vitro investigation of nanoparticular formulations

In this study the CERO 3D Incubator & Bioreactor was used for the generation of tumor spheroids from human colon cancer cell line HT29-MTX-E12. The...

Learn more

Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies

The paper discusses the use of induced pluripotent stem cells (iPSCs) in various biomedical applications, specifically for toxicity testing. The authors describe their strategies for...

Learn more

Functional differentiation and scalable production of renal proximal tubular epithelial cells from human pluripotent stem

The paper presents a protocol for the large-scale production of renal proximal tubular epithelial cells (PTEC) derived from human pluripotent stem cells (hPSC). The researchers...

Learn more
See all Publications