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Publication: The Multifunctional Role of Poloxamer P338 as a Biofilm Disrupter and Antibiotic Enhancer: A Small Step forward against the Big Trouble of Catheter-Associated Escherichia coli Urinary Tract Infections

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De Angelis et al. used a BioFlux Shear Flow System with silicone bottom plates to investigate the use of poloxamer 388 (P338) as an anti-biofilm compound that can be used to manage catheter-associated urinary tract infections. The group found that a 0.5% P338 solution was able to reduce Escherichia coli volume and area up to 50% and disaggregate biofilms up to 34%.

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